For these comparisons, first, an equal p24 level of the viruses collected at day 8 from the VLP treated macrophages (Fig. 3) and also collected at days 3 from the activated CD4+ T cells (Fig. 2) were used to infect to fresh monocyte derived macrophages pooled from 5 new healthy donors, and we monitored the reverse transcription kinetics for 4 days post infection by measuring the copy number of 2LTR circle DNA, which is the completed reverse transcription product. This evidence concerns the gene CD4 and infection.