Xing and colleagues [20] showed that PGC-1α-deficient glioblastoma cell line treated with N6,2′-dibutyryladenosine 3′5′-cyclic monophosphate (dbcAMP) was characterized by abrogated induction of GFAP expression, mtDNA content, and oxygen consumption rate (OCR), while overexpression of PGC-1α was liked to enhanced GFAP expression, mtDNA content, and OCR. Here, PPARGC1A is linked to glioblastoma.