CIRBP and neoplasm: In the same way, for the purpose of investigating the effect of CIRBP knockdown on BCa metastasis in vivo, pulmonary metastasis models were established by tail intravenous injecting LV-shCIRBP UM-UC-3 cells or LV-NC UM-UC-3 cells, after 4 weeks of injection, the fluorescence of pulmonary metastasis tumor was measured to evaluate the migration capacity.