BD and diabetes local polygenic risk regions also overlapped on chromosome 7 (7p21.3), a region that contains the gene NDUFA4 and has previously been associated with a psychosis phenotype45, and chromosome 17 (17p12), a region containing the genes MYOCD, ARHGAP44, and ELAC2, with no previous associations to mood disorders. Here, ARHGAP44 is linked to mood disorder.