Recent studies by Frattini and colleagues have shown that tyrosine-122 (Tyr-122) of Par14 (referred to as PIN4 in their studies) is phosphorylated in a subset of glioblastoma cases expressing the oncogenic fusion protein FGFR3-TACC3 (F3-T3) [71]. The gene discussed is PIN4; the disease is glioblastoma.