PIN1 and cancer: Although it is possible that this function might occur because of an increase in the fraction of more developmentally advanced glioblastoma cells resembling the migratory neural cells in the healthy brain (e.g., oligodendrocyte and/or astrocyte precursor cells), the lack of information on the cancer cell subtypes in which PIN1 is specifically overactivated leaves the door open to other interpretations, including the possibility that PIN1 might increase the migratory potential of most glioblastoma cell types.