AR and breast carcinoma: On the other hand, they also found that AR expression in ER-negative TNBC breast cancers was significantly associated with increased mortality, as compared with AR-negative, ER-negative TNBC tumors (multivariate hazard ratio (model 3), 1.83; 95 percent confidence interval, 1.11 to 3.01; p = 0.02) [38].