The increase rate in Group A was lower than Group B after coarctation relief 4 weeks later, and diameter was significantly lower at week 15 compared with Group B. Elastin fibers and SMCs destroyed dramatically at week 1, and intimal hyperplasia, elastin fibers and SMCs regeneration were found thereafter, especially after coarctation termination in Group A. The different outcomes of AAA models are worthy of investigation, which indicated that hemodynamic change may play an essential role in the initiation and progression AAA in rabbits. This evidence concerns the gene ELN and triple-A syndrome.