Together with the previous study that ncRNA NBAT1 could negatively modulate growth and metastasis of osteosarcoma cells through suppression of miR-2114, and SOCS6 is targeted by significantly downregulated miR-21-5p in secondary progressive multiple sclerosis25, this study will explore the clinical significance of NBAT1 expression, the role of NBAT1 in the regulation of cellular phenotypes, and its molecular mechanism in BC. This evidence concerns the gene SOCS6 and osteosarcoma.