HMGCR and nervous system disorder: Studies were conducted to evaluate the effectiveness of using antiepileptic drugs (eg, oxcarbazepine) together with some 3-hydroxy-3-methylglutaryl– coenzyme A reductase inhibitors for prevention of PD and other neurological diseases, and the experiments showed that the dopaminergic effect of oxcarbazepine is useful in the treatment of PD [45].