TRIM28 and neoplasm: Furthermore, we found that the expression level of MAGEC2 correlates positively with TRIM28 expression in MAGEC2-positive hepatocellular carcinoma tissues, while there was no significant difference for the average score of TRIM28 between MAGEC2-positive and MAGEC2-negative tumor tissues (Additional file 3: Figure S3), suggesting that existence of TRIM28 is a necessary but not a sufficient condition for the expression of MAGEC2 in tumor cells.