MMP8 and Hepatic fibrosis: In a model of murine liver fibrosis induced by carbon tetrachloride (CCl4), administration of PRI-724 (the inhibitor of CBP/β-catenin interaction) accelerated the resolution of liver fibrosis accompanied by an increase in MMP-9, MMP-2, and MMP-8 levels in intrahepatic leukocytes [21].