In the present study, we observed that antroquinonol D induced CCND2 expression in breast cancer MDA-MB-231 cells (Figure 5A), and both antroquinonol D and antroquinonol could induce CCND2 expression in lung cancer CL1-5 cells in a dose-dependent and time-dependent manner (Figure 5B,C). The gene discussed is CCND2; the disease is breast cancer.