Mutations in CTNNB1 (p.D32Y) and in the histones biotinylation gene BTD18 (p.L297Q) were shared between tumour and metastasis, whereas mutations in the apyrase gene ENTPD4 (p.R340NfsTer14) and the translocase of outer mitochondrial membrane gene TOMM22 (p.V99I) were identified exclusively in the primary. Here, CTNNB1 is linked to neoplasm.