Gooding et al. [121] identified several lncRNAs through an in silico approach to be enriched in DCIS relative to adjacent normal (LINC01562, HCG20, SGO1-AS1, PRNCR1, LINC01206, and BORG). Expression of the lncRNA BORG (BMP/OP-Responsive Gene) was confirmed in patient samples to be enriched in DCIS over adjacent normal and further, over expression supports proliferation in vitro and in xenograft models collectively. This evidence concerns the gene PRNCR1 and ductal breast carcinoma in situ.