Therefore, in this study, the expressions of LC3-II, Atg-5, Beclin-1 in monocytes, and the levels of IL-1β, IL-6 and Scr in the peripheral blood of AKI patients were performed to analyse the changes in these indexes before and after treatment with CRRT, with the aim to find novel indexes for clinical prognosis. Here, IL6 is linked to acute kidney injury.