However, tumors in the AGO2-3KR or AGO2-3KR-pre-miR-19b1 group grew much more slowly than those in the AGO2-WT or AGO2-WT-pre-miR-19b1 group (Fig. 6e), respectively, suggesting the acetyl-mutant AGO2-3KR lost its function in promoting tumor growth. Here, AGO2 is linked to neoplasm.