Moreover, the expression levels of miR-19b were positively correlated with the acetylation levels of AGO2-K493-Ac in pathological stages (Stage I, spearman’s rho = 0.7056, P < 0.0001; Stage II, spearman’s rho = 0.4869, P < 0.0004; Stage III/IV, spearman’s rho = 0.6386, P < 0.0001) and tumor grades (Grade 1, spearman’s rho = 0.6575, P < 0.0001; Grade 2, spearman’s rho = 0.68, P < 0.0001; Grade 3, spearman’s rho = 0.5662, P < 0.0003) (Fig. 7e). The gene discussed is AGO2; the disease is neoplasm.