Furthermore, multivariate survival analysis suggested that Hsp90ab1 expression [P = 0.017; HR = 1.983; 95% confidence interval (CI), 1.130–3.478], AJCC stage (P < 0.001; HR = 4.166; 95% CI, 2.573–6.746) and vascular invasion (P = 0.001; HR = 1.524; 95% CI, 1.177–1.974) were confirmed to be independent prognosis factors of disease outcome in GC patients (Table 1). This evidence concerns the gene HSP90AB1 and gastric cancer.