Recently, we showed that Ng-ACP is important for gonococcal survival challenge not only by purified HL but also by human tears, saliva, and adherent interleukin-8 (IL-8)-treated primary neutrophils, which are heavily recruited to sites of gonococcal infection and constitute the major source of HL that this pathogen might encounter (35). This evidence concerns the gene NRGN and bacterial sexually transmitted disease.