Bioinformatics software prediction (TargetScan) showed binding sites for miR-153 and miR-377 in the 3’UTR of FOXR2 mRNA, indicating that miR-377 and miR-153 may regulate the permeability glioma conditioned normal BBB by adjusting the expression and function of FOXR2. Here, FOXR2 is linked to glioma.