Our data agree with a previous report conducted in adult patients with cardiorenal syndrome type 1, which was a retrospective analysis of pooled data from ten prospective observational studies of neutrophil gelatinase-associated lipocalin (NGAL) and demonstrated that in the absence of a diagnostic increases in sCr, NGAL can be used to identify patients with subclinical AKI who have an increased risk of adverse outcomes [15]. Here, LCN2 is linked to acute kidney injury.