PECAM1 and neoplasm: As shown in Fig. 3a, immunohistochemical images showing CD31 expression changes in tumor tissue in different treatment groups showed that a high level of MVD was found in the MTD NVB + Endo group, MTD NVB group, and ctrl group, whereas a lower MVD value was observed in the MET NVB group, Endo group, and MET NVB + Endo group.