In women not treated for osteoporosis, among all the studied variables, the total body mass was the one that best correlated with all sites of bone mass: LS r = 0.427 (p = 0.000), FN r = 0.490 (p = 0.000) and TF r = 0.496 (p = 0.000). The gene discussed is FN1; the disease is osteoporosis.