MMP9 and Dravet syndrome: For MMP-9, the concentration was higher in the US and DS plaque as compared to the control left CCA (0.66±0.17 ng/mg vs. 0.44±0.10 ng/mg vs. 0.15±0.05 ng/mg; US vs. control p<0.01; DS vs. control p<0.05; Fig 5C), however, a statistical significance could not be established between US and DS plaques.