By contrast, we observed a significant increase in PD-1 expression (as assessed by PD-1 MFI) on both CCR7- and CCR7+ cells within CXCR3+CCR6- cTFH (gating strategy Fig 6A) after HBV in HC, but not in CKD (Fig 6B and 6C). This evidence concerns the gene CCR7 and chronic kidney disease.