Intriguingly, we found that high CTHRC1 expression conferred worse DFS (Figure 1E2; P = 0.004) and OS (Figure 1F2; P < 0.001) in the colon cancer cohort, but this association was not observed for DFS (Figure 1E3; P = 0.274) or OS (Figure 1F3; P = 0.345) in the rectal cancer cohort. This evidence concerns the gene CTHRC1 and malignant colon neoplasm.