Univariate analyses indicated that CTHRC1 protein expression correlated with DFS only in patients with colon cancer (P = 0.003, Table S2), whereas CTHRC1 expression was correlated with OS in patients with colorectal (P = 0.002) or colon cancer (P = 0.000) but not rectal cancer (Table 2). Here, CTHRC1 is linked to rectal cancer.