Other mechanism that could use Salmonella enterica to activate immune response is enhancing the expression of connexin 43 (Cx43) [99], a protein associated to B and T lymphocyte activation [100], and promotes the cross-presentation of tumor cell antigens by dendritic cells [101], through the formation of gap junctions that allow the passage of preprocessed tumor cell peptides into the dendritic cell for adequate presentation by MHC class I [99], thus favoring the CD8+ T antitumor lymphocytes (Figure 2(c)). Here, CD8A is linked to neoplasm.