This was confirmed by whole-genome sequencing (WGS) and whole-exome sequencing (WES) of C57BL/KaLwRij mice indicating that SAMSN1 deletion is important for MM predisposition of C57BL/KaLwRij mice and that SAMSN1 is a potential tumor suppressor gene29. This evidence concerns the gene SAMSN1 and neoplasm.