KLK3 and cancer: Based on changes in men with and without cancer in the finasteride arm, these results suggest that an inflation factor of 1.33 = 100/(100–25%) for PCA3, (i.e., inflating PCA3 values by 33%) would make them comparable for recommended thresholds; as expected, an inflation factor of 2.0 = 100/(100–49%) for PSA would be appropriate.