LASP1 and breast carcinoma: LASP1 is located on the chromosome 17q21, a region often mutated or amplified in 20–30% of breast cancer patients and in the neighborhood of the proto-oncogene c-ERBB2 or human epidermal growth factor receptor 2 (HER2) (2) and the breast cancer susceptibility gene1 (BRCA1) (3).