In addition, it's reported that dredging the bowels (DB) herbs including RRR, Zhishi (Fructus Aurantii Immaturus, FAI), Roucongrong (Herba Cistanches, HC), Maidong (Radix Ophiopogonis, RO), and Yujin (Radix Curcumae, RC) could significantly decrease AChE activity whereas increase ChAT activity and ACh content in the hippocampus of AD rats and act anti-aging effects [25, 26]. This evidence concerns the gene CHAT and Alzheimer disease.