However, while GLP-1 receptor (GLP-1R) agonistic agents are effective medicines for T2DM, some unavoidable side effects include nausea, vomit, autoimmune hepatitis, acute kidney injury, pancreatitis, and pancreatic cancer (Prasad-Reddy and Isaacs, 2015). This evidence concerns the gene GLP1R and familial pancreatic carcinoma.