Furthermore, in vitro invasion assays revealed that medulloblastoma cells overexpressing NICD1 are more invasive in Matrigel chambers (Supplementary Fig. 8a–c) and express higher levels of SNAI1 and VIM, which are known to be expressed in metastatic cells (Supplementary Fig. 8d). The gene discussed is SNAI1; the disease is medulloblastoma.