Indeed, in our cohort, 86% of the tumor samples (36/42) evaluated were positive for the presence of GOAT enzyme by IHC (Fig. 2b), wherein 40% of the tumor cases (17/42) presented a strong staining (2 + or 3 + ) for GOAT compared to NTA tissue (Fig. 2c, d). This evidence concerns the gene MBOAT4 and neoplasm.