To report the expression changes of IL-17A and NLRP3 inflammasome, expression levels of NLRP3 in 3T3 (mouse fibroblasts), CT-26 (mouse colon carcinoma) and EL4 (mouse lymphoma) cells were comparatively tested to that from the stimulation of LPS, IFN-γor ionomycin (Fig. 6A). The gene discussed is NLRP3; the disease is colon carcinoma.