NFE2L2 and inherited lipid metabolism disorder: Our recent studies1,2 have demonstrated that sericin improves dyslipidaemia and liver or heart mitochondrial architecture via its anti-oxidative activity, as characterised by the reduction in mitochondrial reactive oxygen species, downregulation of malondialdedhyde (MDA) and upregulation of nuclear factor erythroid 2-related factor (NRF-2).