VCAN and hepatocellular carcinoma: Interestingly, transgenic mice expressing the versican 3’-UTR expressed high levels of the versican isoforms V0 and V1 and develop HCC, suggesting that the versican 3’-UTR functions as a competitive endogenous RNA to induce the development of HCC by regulating miRNA activity to ensure high versican V1 expression and hepatocarcinogenesis [122].