GPRASP1 and Anxiety: This study showed that (i) social defeat stress induces anxiety-like behaviors in spontaneous locomotor activity test or EPM test in defeated mice, (ii) altered submissive, social, and neutral behaviors in susceptible mice, and (iii) altered expression levels of D2 receptor isoforms (D2L and D2S) and intracellular trafficking proteins like Rab4 and GASP-1 in AMY brain region of susceptible mice.