Because we wished to capture SNPs in regulatory elements that are present in multiple prostate cancer subgroups, as well as in normal prostate cells, we performed H3K27Ac and CTCF ChIP-seq in two non-tumorigenic prostate cell populations (PrEC and RWPE-1) and five prostate cancer cell lines (RWPE-2, 22Rv1, C4-2B, LNCaP, and VCaP). Here, CTCF is linked to prostate cancer.