To determine if deletion of the region encompassing CTCF site 3, which anchors the larger loop but does not have a PCa risk-associated SNP nearby, also affected expression of KCNN3, we created clonal 22Rv1 cell populations having homozygous deletion of a 913-bp region encompassing CTCF site 3. Here, KCNN3 is linked to posterior cortical atrophy.