Therefore, it is important to dissect out whether the lncRNAs regulate gene expression by functioning in cis or whether they act in trans. One of the recently reported Cancer Testis noncoding RNA, Thor, was shown to function as an oncogene by binding to an RNA-binding protein (RBP), insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1), causing stabilisation of its target mRNAs like insulin-like growth factor 2 (IGF2) and CD44 [54]. This evidence concerns the gene CD44 and cancer.