RAG2 and acute lymphoblastic leukemia: Increased expression of Notch targets her6/9; cooperation with rag2-EGFP-bcl-2 increases onset/incidence, survival and resistance to irradiation (Chen et al., 2007); enhances T-ALL progression in combination with rag2:cMyc, does not increase LSC frequency, molecularly similar to human disease (Blackburn et al., 2012)