Our data showed that B-ALL cells migrated in response to CXCL12 stimulation, and that migration through 5 μm pore transwell membranes in response to a CXCL12 gradient was significantly impaired in both mDia1 KD B-ALL cell lines (Figure 3B and Supplemental Figure 2B). Here, CXCL12 is linked to acute lymphoblastic leukemia.