TRAF2 and mantle cell lymphoma: Notably, although not cataloged in TCGA, mutations of TRAF2 are recognized as one of the most frequent somatic mutations in mantle cell lymphoma (MCL, 6.1%, 10/165) (99, 100, 101) and diffuse large B-cell lymphoma (DLBCL, 6%, 6/101) (Figure 1B) (102).