KRT18 and metabolic dysfunction-associated steatohepatitis: Subsequently, serum concentrations of these miRNAs were used as inputs into a relatively simple scoring system with a range from 0 to 3, which could be used for a non-invasive prediction of NASH either alone, or in combination with similarly scored levels of cytokeratin-18 fragment Asp396 (CK18-Asp396) that was previously described as a biomarker of NAFLD progression (Younossi et al., 2008).