Recent evidence suggests mGlu7 receptor involvement in the pathology of schizophrenia, as several polymorphisms of gene encoding this receptor have been found in different populations, for example, significant transmission distortion of rs17031835 in intron 1 of GRM7 in Indonesian sib-pair families (Ganda et al., 2009), 14 single nucleotide polymorphisms (SNPs) in GRM7 of Han Chinese population (Li et al., 2016) or synonymus polymorphism (371T/C, rs3749380) in exon 1 of GRM7 in Japanese patients with schizophrenia (Ohtsuki et al., 2008). The gene discussed is GRM7; the disease is schizophrenia.