IGF1 and Cognitive impairment: For serum IGF-1 levels, the Q1 and Q2 groups had significantly greater odds to be with cognitive impairment (OR 8.43, 95% CI (2.4 ± 4.9), P < 0.001 and OR 3.01, 95% CI (0.3 ± 1.2), P = 0.03), while the odds for the Q3 group was OR 2.9, 95% CI (0.59 ± 1.4), p = 0.7 (Table 2).