To determine whether decreased RORA expression in OSCC was caused by the onco-related miRNAs, we selected five miRNAs (miR-503-5p, miR-450b-5p, miR-27a-3p, miR-181a-5p, and miR-183-5p) which linked to tumor proliferation in a variety of cancers, to evaluate their regulation effects on RORA. Here, RORA is linked to neoplasm.