In the intestinal mucosal biopsies of patients with CeD, 7 genes were upregulated (HLA-DRB4, STAT1, TFRC, TGM2, TNFSF13B and ACOT7) and 497 genes were found to be downregulated in the intersection set of CeD vs. FDR and CeD vs. controls (Supplementary Figure 2C, D). The gene discussed is TFRC; the disease is cranioectodermal dysplasia.