CSF2 and neoplasm: The previous studies have shown that tumor cells produce oxysterol [16], C-X-C motif chemokine ligand 5 (CXCL5) [17], hyaluronan fragments (HA) [18], granulocyte-macrophage colony stimulating factor (GM-CSF) [19], and macrophage migration inhibitory factor (MIF) [20].