ELOVL5 and type 2 diabetes mellitus: Given the role of adipose tissue in the development of T2D, we studied epigenome-wide DNA methylation differences (especially “genetically independent” DMR) within genetically identical twins (stage I) and identified T2D-associated giDMR (cg18681426) in the ELOVL5 gene across ethnic groups (stage II) (Table 1).