We studied the role of IL-17A in TSLP production in a 16HBE cell line stimulated with ISs from COPD, HS, and HC subjects, and our results show an increase in TSLP production in 16HBE cells stimulated with ISs from COPD subjects compared with cells treated with ISs from HC or untreated cells. This evidence concerns the gene IL17A and chronic obstructive pulmonary disease.